"Despite repeated recommendations to limit benzodiazepines to short-term use (2-4 weeks), doctors worldwide are still prescribing them for months or years. This over-prescribing has resulted in large populations of long-term users who have become dependent on benzodiazepines."
Ain't that the truth. Also true that many of them are elderly and develop dementia while using benzos such as lorazepam and diazepam (brand names Ativan and Valium, respectively). Recently published research confirms that elders taking benzos develop dementia at higher rates.Ashton, H. (2005). "The diagnosis and management of benzodiazepine dependence."
Unfortunately, many elders are allowed to keep taking their benzos, despite caregivers and others noticing progressively worse cognitive impairment (doctors often don't seem to notice).
It's one of the many crying shames in medicine that is far more common than it should be, and I came across it this week, when a friend of the extended family phoned me from New York, to ask for advice about her 80 year-old husband.
We'll call them Mr. and Mrs. X. She has been noticing memory problems for five years, and Mr. X's problems have been getting worse. He is a long-time Ambien user who was switched to nightly lorazepam two years ago. (Somebody thought lorazepam sounded less dangerous.) Now, Mr. X has chronic problems with memory, learning, organization, and confusion, although he remains independent with his ADLs. And he has trouble recognizing his wife at times, especially in the morning. Coincidence? I think not.
When I pointed out that lorazepam is one of the drugs that geriatricians love to hate, and explained why, she asked me a variant of what I perhaps should start calling "the question:"
"But why didn't any of the doctors we see do something about this?"
As I mentioned in my previous post, some of it is is a lack of geriatric knowledge: many doctors just don't realize how much worse benzodiazepines can make an older person.
But it's also due to a lack of technology. Specifically, physicians in clinic are lacking access to technology to help make a benzodiazepine taper feasible and efficient for both doctor and patient.
What kind of technology am I talking about? Well, for the purpose of this blog, I would define technology quite broadly, as any system, tool, or electronic technology that helps one acheive a task faster and more consistently.
For instance, a pretty basic technology in fairly wide use would be clinical decision support.
But UpToDate.com, arguably the most widely-used source of clinical decision support, has no topic page explaining how to taper benzodiazepines. Never mind a patient information page on the risks of benzos (providing such a resource has been shown to improve taper success), or some kind of worksheet or other system to help patients reduce their dosage and keep track of relevant symptoms.
In other words, if you are a knowledgeable and conscientious physician, and you decide to propose a benzo taper to the patient, you have virtually no help available. You'll need to have a lot of time, and hopefully some personal experience to draw on.
In the outpatient setting, when doing something for a patient takes lots of time, physicians tend to avoid doing it. Obvious, but true.
And now can you help a fellow geriatrician out? Does anyone have some good patient engagement materials to help support Mrs. X as she tries to help Mr. X taper his lorazepam? It would be so nice if he could resume recognizing her most mornings...
(Many thanks to Mrs. X, who gave me permission to use this true story in GeriTech.org)